Viagra May Prevent or Treat Dementia

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January 12, 2022 · 7:00 AM

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Viagra (one model identify for generic sildenafil) is used to deal with erectile dysfunction and pulmonary hypertension. I guess that utilization for ED is much extra widespread than for pulmonary hypertension.

From an article printed in Dec 2021 by National Institutes of Health:

…the group analyzed insurance coverage claims information from greater than 7 million Americans. They discovered that the folks (principally males) who took sildenafil had been 69% much less more likely to develop AD [Alzheimer’s Disease] over 6 years than those that didn’t take the drug. This affiliation between sildenafil and AD held after adjusting for intercourse, age, and different ailments and circumstances.

To perceive how sildenafil would possibly have an effect on AD, the researchers grew neurons from stem cells derived from AD sufferers. Exposing the cells to sildenafil led to elevated progress of neurites, which join neurons to one another, and decreased tau phosphorylation, an early biomarker of AD.

Taken collectively, these outcomes present an affiliation between sildenafil use and decreased AD danger. But the researchers emphasize that they haven’t proven that sildenafil prevents or reverses AD.

These issues normally don’t pan out, however one can hope. How typically had been these guys taking viagra? Once a month? Twice per week? To deal with erectile dysfunction, sildenafil is usually taken as wanted one hour earlier than sexual exercise. A typical dose for pulmonary hypertension is 20 mg by mouth thrice a day, day-after-day. Would this drug have an effect on dementia in women? As they are saying, additional research are wanted.

Steve Parker, M.D.

front cover of Conquer Diabetes and Prediabetes

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